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DOI: 10.1021/ci034243x The ESOL method thus has five tunable parameters: We used Crippen cLogP , as implemented in RDKit, and fit ESOL parameters using an implementation by Pat Walters

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Compound G613 promotes the apoptosis of MCF-7 cells by inhibiting the formation of the p53-MDM2 complex and upregulating p53 expression [50]

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Under physiological conditions the potential for free radical-mediated damage is kept in check by the antioxidant defense system (AODS), comprising a series of enzymatic and non-enzymatic components

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Hailes, H

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