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This dysregulated metabolism creates an environment characterized by persistent oxidative stress, chronic inflammation, and altered energy signaling, which collectively drive fibrosis and cellular transformation (Ramaite and Nkadimeng, 2025)

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Its anti-inflammatory activity had been observed in cellular and animal models, but the precise metabolic mechanism specifically how it modulates Toll-like receptor (TLR) signalling and downstream inflammatory metabolite production was unknown

BPC-157 (Body Protection Compound-157) is a 15-amino acid gastric pentadecapeptide investigated for its interactions with angiogenesis, nitric oxide signaling, and growth factor receptor pathways