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An experiment showed that metformin inhibits the immunosuppressive effects of MDSCs and M2-type TAMs in TME by activating the AMPK signaling pathway [100]

Avoid or limit sugar-sweetened beverages, particularly if you have diabetes

Because a significant percentage of RA patients are negative for serologic markers, additional diagnostic methods are actively being developed to help increase diagnostic accuracy, particularly for seronegative RA patients

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