Chemical Society Reviews
When to See Your GP About Nerve Pain and B12 Levels You should arrange to see your GP if you experience: Persistent tingling, numbness, or burning sensations in your hands or feet Unexplained weakness or difficulty walking Balance problems or frequent falls Memory problems or cognitive changes Persistent fatigue accompanied by neurological symptoms Symptoms of nerve pain if you have risk factors for B12 deficiency Recent recreational nitrous oxide use with neurological symptoms Your GP will typically begin with a thorough clinical history and examination, followed by blood tests to measure serum B12 levels
2 Table 2 Clinical Manifestations of Vitamin B12 Deficiency Maternal vitamin B 12 deficiency during pregnancy or while breastfeeding may lead to neural tube defects, developmental delay, failure to thrive, hypotonia, ataxia, and anemia
Urticaria, pruritus without rash, and angioedema have been reported in less than one percent of patients
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