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Semaglutide is a synthetic version of this hormone, engineered to remain active in the body for approximately seven days making once-weekly dosing possible

The label recommends IM injection twice weekly at 3 mL per 100 kg bodyweight (around 15 mL for a 500 kg horse), with the final dose given 46 hours before hard or fast work

Semaglutide helps manage appetite during this phase, but it doesn't prevent metabolic adaptationincreasing physical activity, strength training, and protein intake can help overcome plateaus