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Graphical Abstract Similar content being viewed by others Introduction The incidence and prevalence of type 1 diabetes is increasing

DMF, via the covalent modification of KEAP1 cysteine residues, leads to reliable NRF2 stabilization, with dose-dependent effects that are cytoprotective at low doses

Most common side effects of topiramate: The common side effects of topiramate include tingling in the arms and legs (paresthesia), drowsiness or fatigue, dizziness, nausea, difficulty with memory or concentration, and changes in taste

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[55] Semaglutide exhibits potent systemic anti-inflammatory and antioxidant properties by modulating the SIRT1 and NRF2 signaling pathways