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The finding that TICs, rather than differentiated tumor cells, grow in 3D gels offers a unique opportunity to unveil TIC-specific signaling pathways and therapeutic targets common to various cancer types

Also, in a clinical pilot study, treatment with SFN increased the antioxidant GSH, suggesting a need to explore possible correlations between GSH and clinical/neuropsychological measures and any positive influence that the treatment of SFN could have on neuropsychiatric disorders [26]