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Health 5 , e703e711 (2023)

The differential equations are then solved to determine the steady-state values of the concentrations of all the variables and the steady state rates of all the reactions

The mechanism of toxicity of copper at the cellular level may be a combination of several different copper-sensitive processes that include inhibition of cytosolic enzymes and pro-oxidant effects that damage plasma membrane function and alter oxidative phosphorylation in mitochondria

Mayer ML, Westbrook GL, Guthrie PB (1984)