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In cancer cells, CHAC1 has been shown to influence the response to chemotherapy by modulating redox homeostasis and contributing to the induction of cell death pathways

Analysis of gene expression data has suggested that GHK-Cu may up-regulate genes associated with repair and regeneration while down-regulating genes associated with inflammation and cellular damage

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Surprisingly, omega-3 FAs stimulated both kynurenine (kynurenine/tryptophan ratio) and serotonin (5-hydroxytryptophan) pathways, whereas omega-6 FAs only increased the kynurenine/tryptophan ratio

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