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47, 105, 106 In addition, HCV core protein promotes STAT-1 degradation, inhibits STAT-1 phosphorylation, promotes suppressor of cytokine signaling (SOCS) induction (an inhibitor of JAK-STAT signaling), and impairs interferon-stimulated gene factor-3 (ISGF3), a heterotrimer of STAT-1, STAT-2, and interferon- promoter stimulator (IRF-9) from binding to the promoter regions of interferon-stimulated response elements (ISRE), thereby inhibiting transcription of interferon-response genes

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These three receptors working together create what pharmacologists call a synergistic metabolic cascade

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Accessed 9/19/2014

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Here is how glutathione may support your kidneys: Reducing Oxidative Stress: By neutralizing free radicals within the renal system, glutathione helps keep the filtering units clear and functional

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