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As GSH and GSSG will react spontaneously with each other and with other thiol and disulfide compounds of the cell, in the thioldisulfide exchange reaction, the ratio of GSH and GSSG reflects the general redox properties of the cell

In many ways, this is where the real opportunity lies

Collectively, these studies paved the way for clinical investigation into the feasibility of using pharmacological inhibition of DPP-4 to improve glycaemic control in patients with T2DM

These observations suggest that the actions of DSIP on substance P, beta-endorphin, and corticosterone are indicative of a wider array of biochemical modifications, proposing that DSIP may trigger a cascade of molecular events that may facilitate its stress-modulatory functions