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After four weeks, the diameter of micro vessels at the fingertips and thus microcirculation was significantly increased in 53.8% of the patients supplemented with Pycnogenol compared to 32% of subjects of the placebo group ( supplemented subjects compared to placebo-controlled people in the study

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17 Alternatively, surgery to remove the prolactin-secreting tumor (a non-cancerous tumor in the pituitary gland) has also been shown to successfully lead to remission