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Sci Rep 7(1):2383

Further, a more than two-fold increase in the duration of base rigidity at or above 60% was observed when comparing the response of individual patients to PT-141 versus placebo [15]

Measures were taken to minimise pain and discomfort of the animals in accordance with the Directive 40/2013 (II.14): On animal experiments issued by the Government of Hungary, and the Directive 2010/63/EU On the protection of animals used for scientific purposes issued by the European Parliament and the European Council