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Discuss with the prescribing physician before starting

Endothelin-1 (20 nM) was applied either through the vascular lumen or in the superfusate, and the constriction evoked did not differ significantly (22.3 7.3% constriction when ET1 was applied in the lumen solution compared to 24 5.4% constriction when ET1 was applied in the bath solution)

and working closely with their healthcare provider to address nutritional needs and monitor blood levels

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