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If the dose counter doesn't advance properly, the injection button feels stuck, or you notice medication leaking from anywhere other than the needle tip during injection, discontinue use and contact your pharmacy

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IUDs (Mirena, Liletta, Kyleena, Skyla, Paragard), the birth control implant (Nexplanon), the shot, the patch, and the ring are not absorbed through the stomach, so tirzepatides (Zepbound, Mounjaro) effect on gastric emptying does not apply

The long-term implications of treating developing individuals with potent metabolic modulators remain uncertain, creating both clinical need and regulatory complexity for companies considering pediatric development programs

In the pivotal SURPASS clinical trial program for type 2 diabetes, diarrhea was reported in 13-17% of patients receiving tirzepatide, with rates varying by dose