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The population-based incidence of pigmented lesions is approximately 10-20% (3)

DOI: 10.1111/j.1365-2141.2008.07091.x 9

This could be due to changes in diet, blood sugar fluctuations, or the psychological impact of adjusting to a new routine

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This is called step therapy. Documentation of diet and exercise attempts: Some plans require evidence that lifestyle modifications have been attempted before approving medication