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The multidrug efflux regulator AcrR of escherichia coli responds to exogenous and endogenous ligands to regulate efflux and detoxification

So far, weve seen no toxicity in our preclinical studies. To improve stability and delivery, the researchers modified FN-2012 with a lipid tail to enhance its ability to penetrate cells

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Although T cells recognize tumor cells in the human body and kill them, the interaction between PD-1 on T cells and PD-L1 on tumor cells leads to T cell exhaustion 91,92,93