GLP-1 receptors have been identified in bone mesenchymal stem cells, indicating a broader physiological role for these incretin hormones
Most of what we know comes from patient reports, observational studies, and reasoning from the physiology of weight loss
Severe deficiency can delay the energy rush
In this small cohort, the majority of patients reported subjective symptom improvement, but the lack of rigorous, large-scale randomized controlled trials (RCTs) means that the safety and efficacy profile in humans is not yet fully established
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