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Regulatory agencies will likely play a major role in determining how quickly these therapies become broadly available

Meanwhile, the US Patent and Trademark Office has officially declined to review a separate petition from Empower Pharmacy seeking to invalidate the same foundational Lilly patent

Typical dosage: Oral for GI applications: 250 to 500 mcg daily, in capsule or dissolved in water, taken on an empty stomach Subcutaneous injection for combined GI + systemic effects: 250 to 500 mcg daily near the abdomen Cycle length: 4 to 8 weeks, then 2 to 4 weeks off Limitations: As of early 2026, essentially no randomized controlled trial data exists in humans

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