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In contrast, the level of 8-OHdG in tumor DNA was significantly higher in GSTP1 AA- than GG-genotypes (p value 0.012 in RAN samples

Response: We may consider this commenter's request in future rulemaking

10.1002/phar.1890 137 FournierE.LevequeM.RuizP.RatelJ.DurifC.ChalanconS.et al

In rats, lutein significantly and dose-dependently boosted the activity of phase II enzymes, including GST and uridine diphosphate (UDP) glucuronyl transferase