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[4] Oertel W, Eggert K, Pahwa R, et al

Distribution Semaglutide absolute volume of distribution is approximately 8 L in patients with type 2 diabetes

These figures represent least-squares mean percentage changes from baseline body weight, and the results in the higher-dose groups were statistically significant compared with placebo

Thus, the conjugate seemingly harnesses the dual pharmacological benefits of hypothalamic GLP-1 receptor agonism and NMDA receptor antagonism while mitigating adverse behavioural effects linked to the latter