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It drives inflammation, insulin resistance, cardiovascular disease, and type 2 diabetes

The rationale is that GLP-1 agonists can reduce B12 absorption over time, and supplementing directly in the injection addresses this proactively

All clinical decisions regarding semaglutide therapy and monitoring protocols should be made by qualified healthcare providers based on individual patient assessment

This transition could help in sustaining motivation and adherence to treatment over the long term. This maintenance approach is currently being investigated

Once-weekly formulations (semaglutide, dulaglutide) can be injected morning or night on the same day each week, whilst twice-daily exenatide must be given within 60 minutes before main meals