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The long-term presence of senescent cells has been linked to aging and skin diseases.82 Animal studies have shown that the destruction of senescent cells may prolong survival and reduce carcinogenesis and the incidence of age-related diseases.83 Selective agents targeting senescent cells in the dermis hold promise as a treatment for aging

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Intervention and Placebo The intervention group received CRWP, commercially available as Immunocal and provided by Immunotec Inc

& Kozarich, J