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The 4-week phases exist for a reason

Ethical responsibilities and 3Rs Although times are changing, especially following the FDAs announcement to phase out animal testing in favour of human-relevant methods, in vivo testing remains a crucial part of preclinical development

Its also important to note that for patients using Wegovy to reduce heart attack and stroke risk which Australias Therapeutic Goods Administration recently approved it for theres no evidence that cardiovascular benefits will be achieved at lower-than-recommended doses

Davies, M., Faerch, L., Jeppesen, O

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