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The protocol (Supplementary Appendix A) was developed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines [6] and has been published on PROSPERO (ID: CRD420251051447)

Ipamorelin is a growth hormone secretagogue at the ghrelin receptor, noted in the research literature for its selectivity, since it releases growth hormone with little effect on cortisol or prolactin in reported studies

You'll need strong medical documentation showing: (1) you tried Wegovy or other covered medications but they didn't work for you, or (2) you have medical reasons why you can't take the alternatives, or (3) you're requesting coverage for sleep apnea rather than weight loss

(2023) 64:S37993