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To prevent postural symptoms , patients should adopt careful postural changes rising slowly from lying to sitting, pausing briefly, then standing gradually whilst holding onto a stable surface

For patients with BMI 35 kg/m (regardless of comorbidities) or BMI 30-34.9 kg/m with metabolic disease, bariatric surgery consultation may be appropriate, according to 2022 American Society for Metabolic and Bariatric Surgery guidelines

For some, this less frequent dosing makes the injection route more convenient

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When to Contact Your Doctor or Pharmacy If any of these conditions are present, you should contact your pharmacy or the prescribing doctor before using the medication