Melatonin is an endogenously synthesized indoleamine well known for its potent antioxidant effect that exerts a beneficial action in many pathological conditions, although studies on its clinical application in humans as a potential anticancer agent are limited
Importantly, supplementation can **increase** measurable NAD+ metabolism: in a 2018 randomized, placebo-controlled crossover trial published in Nature Communications by Martens and colleagues at the University of Colorado Boulder (24 healthy middle-aged and older adults), 1,000 mg/day of the NAD+ precursor nicotinamide riboside (500 mg, twice daily) elevated NAD+ in blood cells by roughly 60% versus placebo over 6 weeks, with no serious adverse events reported
From the article: Vitamin C is an unstable molecule and it can easily break down into a different molecule that doesnt help the skin, said Dr
By comparison, other studies have shown an increase in serum selenium levels in patients with vitiligo compared with the control group [97]
When I flagged it with my GP he said oh, thats just your B12 , nothing you can do about it What