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In this review, we emphasize on (1) GSH depletion as a fundamental risk factor for diseases like chronic obstructive pulmonary disease and atherosclerosis (ischemic heart disease and stroke), (2) importance of oxidative stress and antioxidants in SARS-CoV-2 infection and COVID-19 disease, (3) significance of GSH to counteract persistent damaging inflammation, inflammaging and early (premature) inflammaging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses in younger individuals, and (4) new therapies that include antioxidant defenses restoration

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Incorporation of antioxidants has been shown to further improve stability profiles of retinol-containing delivery systems

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Hum Reprod Update 4(5):741751 Sousa Gers A, Simmons A, Drakesmith H, Aulicino A, Frost JN (2020) The battle for iron in enteric infections