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In a post-hoc analysis of the published SURPASS trials, the change in systolic blood pressure was greater for tirzepatide versus the comparators of the trials (tirzepatide 5 mg: -5.1 to -1.3 mmHg, tirzepatide 10 mg: -6.5 to -1.7 mmHg, tirzepatide 15 mg: -11.5 to -3.1 mmHg) [65]

Investigators identified 1,137,300 patients with IBD, including 70,303 GLP-1 RA users and 1,066,997 non-users

For three or more groups, one-way ANOVA with Bonferroni multiple comparison were used for parametrically distributed data

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