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e Severe hypoglycemia was defined as an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or other resuscitative actions and during which plasma glucose concentration may not have been available, but where neurological recovery following the return of plasma glucose to normal was considered sufficient evidence that the event was induced by a low plasma glucose concentration

10.1093/jat/20.1.55 18 KatayamaH.MizukamiK.YasudaM.HataeT

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Trial Design The SMA CARNI-VAL trial was a multi-center phase II trial of CARNItine and VALproic acid in patients with spinal muscular atrophy

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