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Under physiological conditions, autophagy inhibits apoptosis by clearing damaged mitochondria, but in PD, -syn aggregation binds to Beclin-1 to block autophagosome formation [171,214], leading to the accumulation of pro-apoptotic factors

All four of these GLP-1 medications (Semaglutide, Liraglutide, Dulaglutide, and Tirzepatide) are approved by CDSCO (Central Drugs Standard Control Organization) in India for managing diabetes, with Semaglutide and Liraglutide being common choices for weight management

Peptides mentioned may be prescribed off-label and require medical supervision

Fucoxanthin could stimulate the -oxidation activity and inhibit the phosphatidate phosphohydrolase activity resulting in a decrease in the hepatic lipid droplet accumulation [12]

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