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Materials and methods Study approval and registration The investigator-initiated GSH-MAP study (ClinicalTrials.gov Identifier: NCT 03596125) was conducted in the Department of Obstetrics (2018-2021), funded by the University-Hospital of Nantes, and approved by the medical ethical committee ( CPP-EST I , N2017/65), besides the National Agency for the Safety of Medicines and Health Products (N EudraCT 2017-003999-31)

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278,279,280 About 70% of NMOSD cases are caused by AQP4 auto-antibodies, which after entering the nervous tissue damage astrocytic endfeet rich with AQP4 channels

In regards to intestine peptide, bacteriostatic water should be the preferred method for reconstitution due to its ability to provide an environment conducive to preserving the longevity and stability of the peptide molecules over time