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F.et al

70 Furthermore, pitch-matching experiments revealed a close correspondence between tinnitus pitch and audiogram edge frequency in tonal tinnitus, supporting the notion that cortical reorganization at the edge of hearing loss may influence perceptual characteristics

Decreased mitochondrial function greatly contributes to feelings of tiredness, weakness, and health challenges

This creates constant energy demand, leading to a massive influx of oxygen and the production of reactive oxygen species (ROS) that can damage the very cellular machinery that powers the cell

Moreover, preclinical studies revealed that ferroptosis inducers contribute to the enhanced efficacy of immunotherapy [125] and chemotherapy [126]