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Given that the transcription factor ATF3 induces P21 CIP expression while high c-Jun activity represses P53-mediated P21 CIP induction, 38, 39 the precise c-Jun/ATF2 and ERK1/2 activations regulate the transient increase in p21 CIP protein amounts required to stabilize CyclinD/CDK4/6 complexes from 36 to 40 h in WT mice

Hypertension 29 , 757762 (1997)

Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes

After 24 h, cells were stained with C11-BODIPY, and relative green and red fluorescence was determined (n = 6 technical replicates from 2 independent experiments