Notes on vitamin B12 A larger version of this table can be found in the Google spreadsheet B12 Doses and Absorption
Fat Loss & Metabolic Enhancement (Weight Management) Dosage: 300500 mcg per day, injected subcutaneously (SC) Cycle: Continuous use for 812 weeks, followed by a 4-week break Administration: Best injected in the morning or pre-workout on an empty stomach Stacking: Can be combined with CJC-1295 (w/o DAC), Ipamorelin, or Tesamorelin for enhanced GH-related fat loss Expected Benefits: Increased fat burning, improved energy expenditure, enhanced metabolic function 2
10.1089/acm.2006.12.881 Summary Keywords vitamin B12, efficacy, bioavailability, therapeutic approaches, meta-analysis, cobalamin Citation Mazur M, Ndokaj A, Salerno C, Vallone J, Ardan R, Bietolini S, Carrouel F, Wilk A, Sarig R, Ottolenghi L and Bourgeois D (2025) Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis
For some individuals, vitamin B12 injections may be recommended where deficiency has been identified or absorption is impaired
Caffeine is metabolized more slowly in pregnant individuals, with a half-life of about 15 hours in pregnant individuals compared to about five hours in nonpregnant women
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