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The following adverse reactions have been identified during postapproval use of LANTUS

We also saw more reports of hypersensitivity-type reactions, such as urticaria, than we anticipated, which raises interesting questions about possible immune-related mechanisms. The researchers also calculated the proportional reporting ratio (PRR) of adverse event rates between GLP-1 receptor agonist and DPP-IV users

Immunoprecipitation analysis of rat pancreatic islets identified this precursor as an 18,000 molecular weight (MW) protein, now classified as proglucagon [34]

Int J Mol Sci 20:1477

10.1186/s12933-025-02767-9 11 CollaboratorsG