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Published findings describe effects on genes associated with antioxidant response (Nrf2 pathway), DNA repair mechanisms, ubiquitin-proteasome pathway components, and inflammatory signaling cascades

[DOI] [PubMed] [Google Scholar] 64.Coll A.P., Chen M., Taskar P., Rimmington D., Patel S., Tadross J.A., Cimino I., Yang M., Welsh P., Virtue S., et al

All use should follow medical guidance and the official prescribing information

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Tirzepatide (MD: 10 kg, 95%CI: 12, 8.2), semaglutide (MD: 3.8 kg, 95%CI: 4.9, 2.7), EBID (MD: 2.8 kg, 95%CI: 4.2, 1.4), liraglutide (MD: 2.1 kg, 95%CI: 3.2, 1.1), lixisenatide (MD: 2.0 kg, 95%CI: 3.3, 0.75) and dulaglutide (MD: 1.2 kg, 95%CI: 2.1, 0.25) showed statistically significant reduction in weight from baseline in comparison to traditional antidiabetic drugs (S8 Fig)