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Sulfonylureas also frequently need reduction or discontinuation

Scientists are also targeting metabolic functions beyond cholesterol, because the brain handles energy differently as Alzheimers disease develops

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The overexpression of PGC-1 adeno-associated virus in the brain region of APP23 model mice was observed to result in increased transcription of growth factors, reduced levels of BACE1, and diminished A-mediated neuroinflammation, which collectively led to reduced -amyloid production and neuronal loss (Katsouri et al., 2016)