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Given that IGF1 and cognate receptor are expressed in germ cells, LCs and Sertoli cells [49], intratesticular IGF1 could regulate various aspects of testicular function in both autocrine and paracrine manners

That said, one out of five people generally tend to have a lower than normal level of B12 when measured, putting them at risk for deficiency status

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[DOI] [PubMed] [Google Scholar] 37.Li C, Wu B, Li Y, Chen J, Ye Z, Tian X, Wang J, Xu X, Pan S, Zheng Y, et al

10.1016/j.ecoenv.2023.114831 Summary Keywords bisphenol A, flavonoids, endocrine disruption, oxidative stress, reproductive toxicity, preclinical studies, meta-analysis Citation Okon MB, Fasogbon IV, Swase D, Dangana RS, Makena W, Ojiakor VO, Etukudo EM, Chebet J, Musyoka AM, Ifie SE, Mbyemeire H, Mbina SA, Ugwu OP-C, Oviosun A, Usman IM, Ifie JE, Rangasamy L, Olorunnisola OS, Mounmbegna P, Noreen S and Aja PM (2025) Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies