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Monoacylglycerol lipase: a novel potential therapeutic target and prognostic indicator for hepatocellular carcinoma

In mechanistic studies of how metabolic diseases affect the liver-cell axis, we and others have found that the glucagon-induced amino acid catabolism is impaired in isolated hepatocytes as well as in mice and patients with NAFLD compared with non-NAFLD conditions, whereas the effect on glucose production is not (23,60)

Their findings are not

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