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Small, uncharged and highly lipophilic molecules have a high influx rate across the BBB [307], but PD BBB alterations like thickened basement membrane, altered transporter function/expression and inflammatory conditions could impact the efficacy of a therapy

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p.) linderte reproduzierbar die Haloperidol- und Fluphenazin-Katalepsie (Haloperidol 0,625, 1,25, 2,5, 5,0 und 10,0 mg/kg b