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It was shown that aged or/and damaged RBCs are sequestrated in the hepatic sinusoid in a PS-dependent way, and the human sinonasal epithelial cells (HSECs) mediate the recognition and the binding of damaged RBCs in a PS-dependent manner via stabilin-1 and stabilin-2 (pro-phagocytic signals and ligandligand interactions) [275,276,277]

Although -carotene, retinol, and lutein supplements theoretically have beneficial health impacts, the studys authors found, in a review of the long-term consumption of these nutrients and cancer risk, that it may lead to an increased risk of lung cancer (Satia et al., 2009)