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Physiologically, CDKN2A encodes two proteins p16 Ink4a and p14 Arf through distinct translational programs

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The most commonly reported side effects in Phase 2 trials were gastrointestinal, including nausea, vomiting, diarrhoea, constipation, and decreased appetite

These markers indicate that the patients' body's defense system might be overly active here, according to the study

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