The findings were reported in the paper, Relative effects of genetically proxied glucagonlike peptide1 receptor agonism on muscle and fat mass: A Mendelian randomization study, published in Diabetes, Obesity and Metabolism
The basolateral carnitine extrusion is less well characterized, but a role of organic cation transporter 2 (SLC22A2 or OCT2) in this process has been proposed (41, 42)
Key mutations in genes such as C24SMT, C5DS, and C14DM lead to the loss of ergosterol and the accumulation of other sterol precursors, which reduce the binding affinity of AmB to the parasite membrane and decrease drug sensitivity (Mukherjee et al., 2020)
When administering the injection in the thigh, it's important to locate the correct spot
Others need adjustments to dose timing, injection technique, or meal composition