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Key finding: Ipamorelin increased VO2max by 14%, improved cardiac output by 18%, reduced exercise-induced fatigue by 22%

Severe Gastroparesis: Individuals with diagnosed severe stomach paralysis, as these drugs further slow gastric emptying

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European Journal of Pharmacology , 960 , 176112

Strober B, Thaci D, Sofen H, Kircik L, Gordon KB, Foley P, Rich P, Paul C, Bagel J, Colston E, Throup J, Kundu S, Sekaran C, Linaberry M, Banerjee S, Papp KA (2023) Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: efficacy and safety results from the 52-week, randomized, double-blinded, phase 3 Program fOr Evaluation of TYK2 inhibitor psoriasis second trial