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In its advice published in December, PBAC noted there was a "significant risk" that people who did not meet the two criteria and particularly those who met one threshold but not the other would seek access to the subsidised drugs and therefore that a "risk sharing arrangement" with the company would be needed to manage the cost to the government

Semaglutide is generally well tolerated by most patients

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Nausea may persist but becomes more manageable, and you'll likely notice reduced appetite as the primary benefit

Author contributions Conceptualization: Zhang Jingwen, Zhuang Zhou