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With regards to safety, the highest dose for CoQ 10 supplementation is 1200 mg daily according to well-designed randomized, controlled human trials, although doses as high as 3000 mg/day have been used in shorter clinical trials (Hathcock and Shao, 2006)

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Unlike NSAIDs, acetaminophen does not inhibit cyclooxygenase in peripheral tissues and, thus, has no peripheral anti-inflammatory affects

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Research indicates preferential accumulation in actively dividing cells and tissues with high metabolic activity, including dermal fibroblasts, keratinocytes, and endothelial cells