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Tompkins, one of the author(s) of this manuscript

This process may represent a compensatory, self-limiting response to oxidative overload, as KYNA reduces oxidative bursts in immune cells and promotes T-cell proliferation [170]

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

In our niclosamide solution approach they are not present and so cannot exert any deleterious equilibrating effects, i.e., the high niclosamide solution concentration is preserved