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It was placed on the FDAs 503A Category 2 bulk-substances list in September 2023, a designation that restricted its use in pharmacy compounding

In addition, the authors thank Lindsay Uglow of Spirit Medical Communications Group Limited for medical writing and editorial assistance (funded by Novo Nordisk A/S) and Christin Lth Hertz of Novo Nordisk for reviewing the manuscript

PMID: 30285179

Nausea is a systemic side effect related to the medication's GLP-1 mechanism, not the injection itself, and usually improves as your body adjusts

12,13,14,15,16,17 Unfortunately, for much of the subsequent 20th century, these concepts became superseded by the neurone doctrine, such that glial responses to CNS disorders were considered to be non-specific, stereotypic, always subsequent to primary neuronal damage and of little functional consequence