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While three forms of cystinosis have been described, the disorder displays a continuum of clinical severity inversely related to the amount of residual cystine-transporting activity

8, 9, 10, 11, 12 these patients and experimental animals have a diminished antioxidant status, 13 which contributes to the accumulating evidence that increased vascular oxidative stress could be involved in the pathogenesis of essential hypertension

Additionally, glutathione is essential for the proper function of lymphocytes and natural killer (NK) cells